Innovation prize winner of many contests, Cardiawave was created at the end of 2014 as a result of a partnership of over 6 years between the Langevin Institute, a world leader in ultrasound imaging and therapy, and the Georges Pompidou European Hospital (HEGP), a leader in the field of valve disease and cardiac ultrasound imaging.

Led by an experienced management team with a solid background in industrial and clinical development and backed by an international SAB with Prof. Alain Cribier (inventor of TAVR), Cardiawave has secured over €14m since inception to develop and bring its medical device to the market.

A first paper was published in JACC: Basic to Translational Science in June 2017: Villemain, O., Robin, J., Bel, A., et al. Pulsed cavitational ultrasound softening: a new noninvasive therapeutic approach for calcified bioprosthetic valve stenosis, JACC: Basic to Translational Science, 2 (2017), pp. 372-383.

Cardiawave has won
several awards and contests

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Awards & Honours:

2018 Prize-winner of SME Instrument, Phase 2
European Union

2017 Prize-winner of Worldwide Innovation Contest (CMI), 3rd phase
French government / BPI France

2015 Prize-winner of Worldwide Innovation Contest (CMI), 2nd phase
French government / BPI France

2015 Prize winner of Fondation pour l’Innovation Thérapeutique Béatrice Denys
Turenne Capital (French Investment Fund)

2014 Prize-winner of Worldwide Innovation Contest (CMI), 1st phase
French government / BPI France

2014 Prize-winner of the French National Contest for Innovative Technologies Companies
French government / BPI France


Benjamin Bertrand
CEO, Chairman of the board
Dr. René Spaargaren
Chief Medical Officer
Luc Morisset
Quality and Regulatory Affairs Director
Fabienne Betting
Chief Technical Officer
Michael Vion
R&D Director

Board of Directors

Emmanuel Blanc
Christian Dailly
Business Angel
Jean De Gunzburg
CSO Da Volterra
Armelle Graciet
Director Industrial Affairs SNITEM
François Thomas
Sofimac Innovation

Scientific Advisory Board

Prof. Emmanuel Messas
Head of SAB, Founder, Cardiologist, HEGP
Michael Tanter, PhD
Founder, Physicist, Langevin Institute
Mathieu Pernot, PhD
Founder, Physicist, Langevin Institute
Prof. Mathias Fink
Founder, Physicist, Langevin Institute
Prof. Alain Cribier
Cardiologist & TAVR Inventor
Prof. Ehud Schwammenthal
Cardiologist & CMO Magenta
Dr. Robert Levine
Cardiologist, MGH
Prof. Albert Hagège
Cardiologist, HEGP


Véronique Asty
Office Manager
Marco Cammarata
Mechanical R&D Project Manager
Sergio Cammarata
SW development Project Manager
Aurélien Corbel
Real Time SW Project Manager
Ana Fouquier
Medical Imaging Project Manager
Wojciech Kwiecinski
Ultrasound R&D Project Manager
Zahir Larabi
Tests automatization and Validation Manager
Eric Noël
Electronics R&D Director
Robin Penot
R&D Engineer
Clémence Pupier
Quality & Regulatory Affairs Project Manager
Mathieu Rémond
Preclinical Project manager
Claire Réty
Tests and Validation Engineer
Daniel Suarez
Biomedical imaging Engineer